Abstract
Effect of crizotinib on apoptosis of lung cancer cells was investigated. However, detailed mechanism is still unclear. Therefore, in this study, crizotinib was used to treat H2228 non-small cell lung adenocarcinoma cells and its effect was observed on cell apoptosis and expression of JAK and STAT protein, so as to explore the effects of crizotinib on lung cancer and the role of JAK-STAT signaling pathways.
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