P5.22 Granulomatous myositis and inclusion bodies myositis in a patient with hepatitis C

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A 54-year-old man diagnosed with hepatitis C presented muscle atrophy and progressive muscle weakness in the lower limbs, resulting in difficulties in walking, with frequent falls without pain or sensibility changes. He was treated with interferon and ribavirin, with improvement of the muscle symptoms. It was performed an electromyography and a muscle biopsy for neuromuscular disease research. Electromyography revealed a myopathic pattern. Muscle biopsy showed sarcoplasmic vacuoles and granulomas with epithelioid histiocytes, lymphocytes and occasional multinucleate giant cells of the Langerhans type within muscle parenchyma.