P4-136: Parkinsonism is associated with probable REM sleep behavior disorder in cognitively normal elderly subjects: The Mayo Clinic Study of Aging

Abstract

and hyperhomocysteinemia) and compared prevalences of these risk factors by gender. And we also compared NIHSS (NIH Stroke Scale) and MRS (modified Rankin Scale) at admission and at discharge. And we surveyed present MRS and BI (Bathel index) by telephone and contrasted with the former. Results: 708 patients were male, aged 17-100 (mean 65.7 years) and 630 were female, aged 27-107 (mean 71.6 years). The female group were older and suffered more frequently hypertension (P 0.05). The male had a slightly younger mean age, more smokers and more family history (P 0.050). The differences of NIHSS at admission and discharge between the two gender groups were statistically significant (P 0.043*). And the oldest age group had significantly poorer long-term outcome represented by MRS and BI than the younger two groups (P 0.000*). The larger infarction size were also related to the poorer short-term outcome (P 0.007*). But the gender and lesion size were not related to the longterm outcome (P 0.050). And the differences of short-term outcome among the age groups were statistically insignificant (P 0.050). Conclusions: Functional outcome represented by BI, neurologic out come represented by MRS was not different between two gender but mean difference was evident. And cognitive burden should be also assessed regarding the dementia outcome from first stroke is over 30%. This observation would lead to differential approaches to prevention of first-ever stroke between two gender.