P3.07-020 Implementation of an International Value-Based Standard Set of Outcomes for Lung Cancer Patients in a Brazilian Center: Topic: Other – Geographical Differences

Abstract

Measurement of value is increasingly important in cancer care, especially in lower-income countries. Grupo COI is a Brazilian private cancer care institution, member of the ICHOM (International Consortium for Health Outcomes Measurement) working group for lung cancer standard set definition. We report here feasibility and results for the first year of implementation. Lung cancer (LC) patients inclusion started on June/2015. Data were prospectively obtained from medical charts and patients interviews. All patients signed an informed consent (IC) and were only included if they would receive entire treatment at our center. ICHOM standard set outcomes included survival, complications during or within six months of treatment, baseline demographic, clinical, and tumor information and patient-reported quality of life evaluation (EORTC QLQ-C30 and QLQ-LC13). A total of 392 LC patients were admitted at COI, but only 120 patients (30.6%) met inclusion criteria. Main reasons for exclusion were partial cycle of care at COI (64.9%) and any treatment started before IC signature (11.3%). Median follow up was 7.9 months and baseline clinical data are presented in Table 1. Patient reported outcomes (PROs) were obtained from paper and phone calls. PROs assessment deviations were reported in 49 patients (38.5%) and reasons for them were application date error (63.2%) and patient or family refusal (36.7%). Cost data are being registered for future analysis.Table 1Baseline Clinical and Demographic CharacteristicsMedian age - years (variation)68 (36 – 91)GenderMale57 (47%)Female63 (52%)Educational LevelPrimary21 (17%)Secondary36 (30%)Tertiary63 (52%)Performance status0-1101 (84%)26 (5%)3-40Non specified13 (10%)HistologyAdenocarcinoma66 (55%)Squamous-cell carcinoma29 (24%)Small cell carcinoma12 (10%)Others13 (10%)StageI-II21 (17%)III29 (24%)IV70 (58%) Open table in a new tab Applying an international value-based outcome standard set at a Brazilian institution is feasible. Based on these first data, improvements on PROs assessment methodology are being considered, like self-report electronic forms. Some inclusion criteria should also be revised to avoid this large number of patients exclusion, in order to reproduce a real-world scenario.