P300 with verbal and nonverbal stimuli in normal hearing adults

Eliane Schochat,Carla Gentile Matas,Camila Maia Rabelo,Alessandra Giannella Samelli,Camila Gonçalves Polo Massa

doi:10.1590/s1808-86942011000600002

Eliane Schochat, Carla Gentile Matas + Show 3 more

Open Access

https://doi.org/10.1590/s1808-86942011000600002

Copy DOI

Abstract

AbstractThe P300 results from focusing attention on rare stimuli in the midst of other frequent stimuli; it tests recent attention and memory, both of which depend on discriminating among verbal or nonverbal stimuli. AimTo compare the P300 with verbal and nonverbal stimuli in normal-hearing adults. Material and MethodA prospective study was made of 15 male subjects aged from 22 to 55, with no hearing complaints. The subjects underwent short and long latency (P300) auditory evoked potentials with verbal and non-verbal stimuli. ResultsThe mean P300 latency with verbal stimuli was significantly higher than the P300 with nonverbal stimuli. The P300 amplitudes were significantly lower for verbal compared with nonverbal stimuli. ConclusionThere were no differences between ears with respect to P300 latencies and amplitudes for both non-verbal and verbal stimuli. Latencies were higher with verbal stimuli; amplitudes had lower values.

Highlights

There were no differences between ears with respect to P300 latencies and amplitudes for both non-verbal and verbal stimuli
Long latency auditory evoked potentials (LLAEP) are recorded electrical responses generated in the thalamus, auditory cortex, and cortical association areas; these structures are involved in discrimination, integration, and attention tasks
P300 with a non-verbal stimulus Table 1 shows the results of P300 latencies and amplitudes after a non-verbal stimulus in the right and left ears

Summary

Introduction

Long latency auditory evoked potentials (LLAEP) are recorded electrical responses generated in the thalamus, auditory cortex, and cortical association areas; these structures are involved in discrimination, integration, and attention tasks. These potentials consist of a series of positive and negative peaks that occur at least 50 ms after a stimulus is initiated, and may be used as a clinical investigation tool to study neural mechanisms of auditory perception in subjects with normal and abnormal central nervous systems[1,2,3,4]. It is thought that the P300 is generated in structures of the frontal cortex, supratemporal auditory cortex, and the hypocampus[7]

Objectives

Results

Discussion

Conclusion