Abstract
Chronic stress yields adverse effects including debilitating depressive-like symptoms in susceptible populations. Neurophysiological data has previously defined a network involved in mediating resilient and susceptible states in response to chronic stress. This neuronal circuit arose from projections between the prefrontal cortex (PFC) and the amygdala (AMY) and its chemogenetic activation induced a rescued stress-resilient state both phenotypically and network-wide. Although this complex PFC-AMY circuit has been previously characterized, it remains unknown which network-specific cell types in the AMY with reciprocal projections with the PFC mediate this circuit.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
