Abstract

Alcohol use disorders (AUDs) affect up to 60% of individuals with bipolar disorder. Despite this, we lack sufficient understanding of mechanisms that contribute to elevated risk for AUDs in bipolar disorder. Altered functional connectivity within ventral prefrontal cortical (vPFC) networks is reported in bipolar disorder and associated with risk for AUDs. This study examined acute alcohol-induced changes in vPFC functional connectivity during emotional processing in young adults with bipolar disorder compared to typically developing peers.

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