Abstract
Background Tumor biomarkers represent an effective tool for diagnostics and follow-up monitoring of patients with non-small cell lung cancer (NSCLC). We focused on predictive and prognostic role of seven following tumor biomarkers: carcinoembryonic antigen (CEA), cytokeratin-19 fragments (CYFRA 21-1), MonoTotal, neuron-specific enolase (NSE), chromogranin A, thymidine kinase (TK) and squamous cell carcinoma antigen (SCCA) in patients with advanced-stage NSCLC treated with pemetrexed-based chemotherapy.
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