P11. Does the choice of spinal interbody fusion approach significantly affect adjacent segment mobility?

Abstract

<h3>BACKGROUND CONTEXT</h3> Previous studies have concluded that LLIF, TLIF, and PLIF with posterior pedicle screw-rod fixation (PSR) provide equivalent stability in cadaveric specimens and are comparable in fusion rate and functional outcome. However, long-term complications, such as adjacent segment degeneration associated with each type of interbody device, are currently unclear. Little is known about the biomechanical effects of interbody fusion technique on the mobility of adjacent segments. <h3>PURPOSE</h3> To investigate the differences in adjacent segment mobility among three types of LIF: lateral lumbar interbody fusion (LLIF), transforaminal lumbar interbody fusion (TLIF) and posterior lumbar interbody fusion (PLIF). <h3>STUDY DESIGN/SETTING</h3> Biomechanical study of range of motion (ROM) at the vertebral levels adjacent to the construct of posterior pedicle screw-rod fixation with different types of lumbar interbody fusion techniques (LIF). <h3>PATIENT SAMPLE</h3> Human cadaveric lumbar spine. <h3>OUTCOME MEASURES</h3> Adjacent segment range of motion. <h3>METHODS</h3> Normalized ROM data at the levels adjacent to L3–L4 PSR fixation with 3 different types of lumbar interbody fusion approaches (LLIF, TLIF, and PLIF) were analyzed. Intact (n=21) and instrumented (n=7 per group) L2–L5 cadaveric specimens were tested multidirectionally under pure moment loading (7.5 Nm). Analysis of variance of adjacent segment ROM among the groups was performed. Statistical significance was set at p<0.05. <h3>RESULTS</h3> Normalized ROM was significantly greater with PLIF than with LLIF in all directions at both proximal and distal adjacent segments (p≤0.02) except for axial rotation at the distal adjacent segment (p=0.07). TLIF also had greater normalized ROM than LLIF during lateral bending at the proximal adjacent segment (p=0.008) and during flexion, extension, and lateral bending at the distal adjacent segment (p≤0.03). Normalized ROM was not significantly different between PLIF and TLIF. <h3>CONCLUSIONS</h3> The choice of lumbar interbody fusion approach influences adjacent segment motion in a cadaveric model. LLIF had the least adjacent segment motion. <h3>FDA DEVICE/DRUG STATUS</h3> This abstract does not discuss or include any applicable devices or drugs.