Abstract
Brain metastases in patients with ovarian carcinoma are extremely rare. Only 1.7% of these patients develop brain metastases. The prognosis in these patients appears to be poor.We report 4 female patients with intracranial single metastase who were treated in our institution within the last 2 years. The age of the patients at time of operation were 43, 66, 74 and 76 years. The interval between diagnosis of ovarian carcinoma and brain metastasis was 3 years in 2 patients, 4 and 7 years. Two patients had supratentorial metastasis in the frontal lobe and the other 2 were located infratentorially in the cerebellum. Histopathological examinations showed typical signs of metastasis of the primary carcinoma. Postoperative outcome was good and further radio- and chemotherapy was performed. Interdisciplinary management with the gynecologists is mandatory. Though brain metastases of ovarian cancer is very rare it has to be kept in mind in the preoperative differential diagnosis and planning of the operation. Mean average age is 54 years and mean interval between diagnosis of ovarian carcinoma and metastases is about 2 years. Median survival time postoperatively is about 6 months.
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