Abstract
Aims & Objectives: To describe clinical and demographic characteristics of pediatric patients with STEC-HUS admitted to the intensive critical care unit from January 1, 2019 to December 31, 2019. Furthermore, the patients were followed up to 2 months after discharge to evaluate the recovery of renal function. Methods: A retrospective case series of pediatric patients whit HUS diagnosed and admitted to ICU. An inclusion criterion was the presence of diarrhea in prodromes and not only the positivity for Stx. Results: In 2019, 31 patients with HUS diagnosted were admitted to Ludovica Children’s Hospital (La Plata – Argentina) of wich 25% (n=8) needed critical care. Mortality in this group was 25% (n=2). In all cases the neurological symptoms were the reason for going to ICU. 7 of 8 patients (87,5%) has colopathy of which 5 were ileostomized (71,4%). Laboratory findings included increase of lactate dehydrogenase level, renal impairment, leukocytosis and schistocytes in all patients. All patients admitted to ICU required dialysis, 25% peritoneal dialysis (n=2) and 75% hemodailysis (n=6). Conclusions: This study suggest that pediatric patients diagnosted with HUS with neurological symptoms has high risk to be admitted to ICU.
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