P01.09: Uterine artery pulsatility index in pregnancies complicated by preterm premature rupture of membranes as predictor of placental vascular complications

Abstract

Increased uterine artery pulsatility index (UtA-PI) is associated with adverse obstetrical outcomes. We aim to study the association of abnormal UtA-PI with placental vascular complications in pregnancies with preterm premature rupture of membranes (PPROM). Ultrasound was performed in women with PPROM from 2015–2017. The mean UtA-PI was calculated by averaging the right and left mean UtA-PI in each patient. At least 5 consecutive waveforms were analysed in each side. UtA-PI ≥ 95th percentile for gestational age (GA) was considered abnormal. The rate of abnormal UtA-PI was compared among women with placental vascular complications and those without such complications. Placental vascular complications included hypertensive disorders of pregnancy (HTNP), small for gestational age (SGA), and placental abruption. Statistical analysis included Fischer exact, Chi-square and Wilcoxon Rank Sum as indicated. A p value < .05 was considered statistically significant. Data is presented as median (quartile ranges) and n (%). P01.09: Table 1. 58 women were included. 12 had placental complications (21%). HTNP occurred in 6 women (10.3%). Four had a SGA neonate (6.9%) and three had placental abruption (5.2%). The rate of abnormal UtA-PI was similar between groups (16% versus 15%; OR= 1.12 [CI=.14-6]). UtA-PI before delivery does not appear to predict placental vascular complications in women diagnosed with PPROM.