Ozone- A Biological Therapy in Dentistry- Reality or Myth?????

Saraswathi V. Naik,Shivani Kohli,Shekhar Bhatia,Sayyad Zohabhasan,Rajeshwari K

doi:10.2174/1874210601610010196

Abstract

The usage of ozone in dentistry has been proposed because of its antimicrobial, disinfectant, biocompatibility and healing properties. In the last decade a number of therapeutic protocols with ozone have been developed to address common dental infections associated with periodontal disease, RCT and caries. Despite these advantages, therapeutic ozone’s application in dentistry is limited because of its possible side effects. Hence, dental practitioners need to know the proper usage of ozone therapy that can provide better patient care and considerably cut down the time and cost of the treatment.

Highlights

Ozone therapy has been used for therapeutic purposes since the 19th century
A study conducted by Baysan proved that the number of bacteria in carious root lesions is considerably reduced by ozone therapy, and that the lesions clinically change to stages in which progression of the caries can be considered to have ceased [27]
A recent Cochrane Review identified 3 randomised controlled trials (RCTs) and two of the three RCTs included in the analysis investigated the effect of ozone therapy on crown lesions, while the third investigated the effect on root lesions and it was concluded that these trials provide no evidence that the application of ozone arrests or reverses the decay process [31] and ozone and photodynamic therapy(PDT) had a minimal effect on the viability of microorganisms organized in a cariogenic biofilm [32]

Summary

Introduction

Ozone therapy has been used for therapeutic purposes since the 19th century. The first mention of ozone was made by Dutch physicist Martin van Marun in 1785, but it was Christian Friedrich Schonbein in 1840, a Professor in University of Basel, who demonstrated the changes of the properties of oxygen with the formation of the particular gas called ozone. Thanomsub et al demonstrated the effect of ozone treatment on cell growth and structural changes in bacteria such as E. Ozone brings about the rise of Po2 in tissues and improves transportation of oxygen in blood, which results in change of cellular metabolism activation of aerobic processes (Glycolysis, Kreb’s cycle, B-oxidation of fatty acids) and use of energetic resources.

Results

Conclusion