Abstract
Oxidative Stress: Role of Eruca sativa Extract on Male Reproduction in Rats
Highlights
Oxidative stress (OS) is a condition that reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and the ability of biological system to detoxify or to repaired the resulting damage (Saalu, 2010; Birben et al, 2012)
Eruca sativa Preparation Ethanolic extract of Eruca sativa leaves was prepared according to the method described by Jin et al (2009), the yield equal of 10 g of extract was stored in a dark sterile screw bottle at (4°C) until used
In follicular stimulating hormone (FSH) concentration in T2 and T3 groups compared to group T1
Summary
Oxidative stress (OS) is a condition that reflects an imbalance between the systemic manifestation of reactive oxygen species (ROS) and the ability of biological system to detoxify or to repaired the resulting damage (Saalu, 2010; Birben et al, 2012). ROS has been linked to the pathogenesis of numerous disease (Alfadda and Sallam, 2012). Previous studies indicated that spermatozoa and seminal plasma contain a battery of ROS scavenger, including enzymes such as SOD, catalase (CAT) and the glutathione peroxidase / redctase system, and a variety of substances such as a tocopherol, ascorbic acid, glutathione, pyrovate, taurine hypotaurine and albumin (Alvarez and Storey, 1989; de Lamirande and Gagnon, 1992). The main source of endogenous ROS in semen are leukocytes (Aitken and Baker, 1995; Gharagozloo and Aitken, 2011) and abnormal spermatozoa (Sakkas et al, 2003). Under pathological condition, January 2017 | Volume 5 | Issue 1 | Page 39
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