Oxidative stress and airway mucus hypersecretion

Abstract

Asthma is a bronchoconstriction reversibility,lung inflammation and airway remodeling for characteristics of chronic airway inflammatory disease.Excessive mucus secretion lead to obstruction of the airway,lung function decline,airway remodeling and increase infection.Excessive reactive oxygen species/reactive nitrogen species (ROS/RNS)produce cause airway inflammation,airway responsieness,airway microvascular high permeability and high airway mucus secretion,and tissue damage and the change of the form.Reduce oxidative stress or increase antioxidant that can reduce airway eosinophils,reduce mucus secretion,reduce bronchial high reaction.Oxidative stress and asthma airway mucus secretion relationship high application were introduced in this paper. Key words: Bronchial asthma; Airway mucus hypersecretion; Oxidative stress