Abstract
Our current research is focused on the kinetics and mechanistic of oxcarbazepine (OXZ) in the presence of sodium-N-chloro-benzene sulphonamide or chloramine-B (CAB) at 308 K in HCl medium. We found that the kinetics of the reaction obeys a first-order dependency on [CAB]0 and fractional order dependence on [substrate]0 and [HCl]. Benzene sulphonamide addition and change in ionic strength have no substantial effect on the rate. Arrhenius plots were used to assess the thermodynamic parameters of the reaction at five different temperatures. Based on the chromatographic and spectroscopic analysis, the oxidation product imine was predicted to have a stoichiometry of 1:1. Based on the observed results, we have deduced the rate law associated with the mechanism.
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