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https://doi.org/10.1016/s0040-4039(00)61578-2
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Cite Journal: Tetrahedron Letters |  Publication Date: Oct 1, 1993 |
 Citations: 37 |
Affiliation: Colorado State University
High diastereoselectivities (93:7) were observed in the biaryl coupling of 2′,6′-disubstituted aryl Grignard reagents of 1 with aryloxazolines 2. The diastereoselectivities observed in the coupling reaction varied primarily as a function of the chelating properties of the ortho substituents on the aryl Grignard reagent.
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