Abstract
Over the last few years, the focus over the ocular delivery system has been increased exponentially. The reason behind this interest may be due to noninvasive nature of this administration route along with its patient compatibility. The side effects associated are also fewer. However maintenance of its efficiency still remains a challenging task for the formulation scientists as there are number of external barriers like tear, blood flow in conjunctiva, blood retinal barrier, film clearance etc. Along with these problems, since the solubility of the drug also affects the efficiency of the formulation, nanosuspension is an attractive approach to resolve these problems. Nanosuspension contains a poorly soluble drug suspended in dispersion medium. This colloidal system improves the poor solubility of the drug to a great extent with alteration of its pharmacokinetic profile, its safety and efficacy.
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