Overview of Non-infectious Uveitis, Mechanisms, Immunopathology, Classification, and General Clinical Findings

Abstract

Uveitis is the inflammation of the anterior, intermediate, or posterior uvea, the pigmented part of the eye. Uveitis can be infectious or non-infectious presented as autoimmune and immune-mediated. Non-infectious uveitis is the most common type of uveitis. It can be idiopathic or secondary to systemic diseases. Differential diagnosis is important, if early diagnosis and treatment are not applied, permanent eye damage can occur. In this review, an overview of non-infectious uveitis is examined with the mechanism, immunopathology, and classification.