Abstract
A cascade of enzymes acting in union is involved in the natural wound healing pharmacology of humans making the process a lengthy one. This in turns necessitates new synthetic molecules effective in accelerating the wound healing process. The present review provides an overview of wound healing potential of the traditionally known compounds together with a comparison of the activity of the conventional compounds with respect to the dalethyne derivatives. Additionally, the present review summarises the antiseptic and the anti-microbial action of the conventional wound healing agents together with a comparison with the dalethyne derivatives. The review further indicates that the Dalethyne derivatives exhibit potent wound healing activity with respect to the traditionally known components which is attributed to their conducive anti-microbial action. However, the present review is an exhaustive one and also refers to some of the experimental data which has been observed in present laboratory experiments. Keywords: Dalethyne, antiseptic, anti-microbial, wound healing
Highlights
Wide array of wound antiseptic has been used in wound care
The purpose of this review is to study the characteristics of commonly used antiseptic in comparison with Dalethyne for wound care
Hemostasis is the first phase of wound healing and is a blood clot formed of thrombocyte aggregation and other blood cells (Enoch et al, 2006)
Summary
Wide array of wound antiseptic has been used in wound care. With recent development of antimicrobial resistance, there is an urgent need in developing a new topical antiseptic. A wound treatment agent need to protect wounded tissue from bacterial infection, reduce inflammation and induce cell proliferation to help in reconstruction of damaged tissue (Kulac et al, 2013). The optimal wound healing agent will protect the tissue from bacterial infection, reduce inflammation, and induce cell proliferation to help with the reconstruction of the damaged tissue (Kulac et al, 2013). It will ideally act as antioxidant because the free radical is considered as the main cause of inflammation in the wound healing process (Mohanty et al, 2012). The review is exhaustive and summarises the wound healing action of the dalyethene derivatives based on the published data
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