Overview of Covid-19 Infection Manifestation in Neuropsychiatry Aspect

Abstract

At the end of 2019 the world was shocked by the corona virus infection pandemic. This virus began with reports of infections in the Wuhan area, China. The death rate from covid-19 infection can reach 3%; however, the mortality rate in critically ill patients with Covid infection is much higher, reaching 61.5%. The main manifestation of covid infection is respiratory tract infection. Corona virus can penetrate central nervous system) and cerebrospinal fluid in less than a week. Histopathological examination of the brain of the deceased Covid-19 showed the potential for SARS-CoV-2 to infect the central nervous system (CNS). Neuro-inflammation can also damage the BBB (Blood Brain Barrier). A number of patients treated with Cocid 19 infection exhibited symptoms of confusion and agitation in the absence of respiratory symptoms or other signs of infection. A recent survey in China showed that 35% of respondents reported psychological distress while 53.8% rated the psychological impact of the pandemic as moderate or severe. The existence of the Covid pandemic not only has a direct impact on infected individuals but has also caused a new wave of psychological stress in society. This study attempts to summarize the neuropsychiatric impact and neuropathological mechanisms of Covid 19 infection.