Outcome of Patients After Radical Retropubic Prostatectomy: A Comparison of Prostate Cancer Diagnosed Using Extended Needle Biopsy Technique vs. Non-extended Needle Biopsy Technique

Abstract

Objective: We evaluated the differences in pathologic findings and outcomes in patients undergoing radical retropubic prostatectomy (RRP) for localized prostate cancer diagnosed by either extended or non-extended prostate needle biopsy techniques. Patients and Methods: Two hundred and seventy eight men with the diagnosis of localized prostate cancer using needle biopsies who underwent RRP were evaluated. Two study groups were identified: the first consisted of 123 patients diagnosed with prostate cancer by the use of extended needle biopsies (10 or more biopsy cores), and the second group consisted of 155 patients diagnosed with cancer by non-extended needle biopsies (9 or less biopsy cores). Median time of follow-up was 45 and 50 months, respectively. Biopsy and RRP specimen characteristics and outcome were compared between the two groups. Results: Patients in the extended biopsy group had a median of 12 biopsy cores Interquartile range (IQR, 10–13; range, 10–16) with a mean of 2.7 cores positive for can...