Abstract
Introduction Neocortical epilepsy in the absence of a tumor or vascular lesion is more resistant to surgical cure, with Class I outcomes relatively less common. We have used an aggressive approach in evaluation and operation. We assess our outcome and prognostic factors. Methods We retrospectively studied 18 pediatric patients with medically intractable neocortical epilepsy caused by focal cortical dysplasia (FCD) operated upon over 3.75 years. All patients underwent monitoring with subdural electrode arrays. Patients had epilepsy for a mean of 4.6 years before operation and a mean age at operation of 6.3 years. Patients have been followed for at least 8 months after resection with a mean of 23 months. Results Fourteen patients (78%) were rendered seizure free. One (5.6%) had residual intermittent simple partial seizures. One had > 95% seizure reduction, and 2 had 80–94% seizure reduction (10%). There was no correlation between seizure outcome and status epilepticus, normal MRI and location of resection. ...
Published Version
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