Ouassima EL Kadiri, Samiha Sabri, Raja Ousalm, Salma Chabli, Ibtissam Zrara Touiti, Mouna Darfaoui, Abdelhamid El Omrani, Mouna Khouchani

Abstract

Rhabdomyosarcoma (RMS) is a malignant neoplasm that originates from undifferentiated myogenic progenitor cells. It is predominantly a pediatric disease, and its occurrence in adults is exceedingly rare. Adult primary RMS of gynecologic origin is an uncommon phenomenon, and the cervix is the most frequently involved site. The incidence of adult primary uterine RMS is extremely scarce. Herein, we present the case of primary uterine RMS in a 59-year-old Moroccan postmenopausal woman who presented to clinic attention with a two-month history of metrorrhagia. The patient received a multimodal therapy comprising a combination of surgery, chemotherapy and radiotherapy with a good clinical and radiological evolution.