Abstract
Osteoid osteoma is a painful, benign and common bone tumor that is prevalent in young adults. The typical clinical presentation consists of pain that becomes worse at night and is relieved by nonsteroidal anti-inflammatory drugs. The most common imaging finding is a lytic lesion, known as a nidus, with variable intralesional mineralization, accompanied by bone sclerosis, cortical thickening and surrounding bone marrow edema, as well as marked enhancement with intravenous contrast injection. When the lesion is located in typical locations (intracortical bone and the diaphyses of long bones), both characteristic clinical and radiological features are diagnostic. However, osteoid osteoma is a multifaceted pathology that can have unusual presentations, such as intraarticular osteoid osteoma, epiphyseal location, lesions at the extremities and multicentric nidi, and frequently present atypical clinical and radiological manifestations. In addition, many conditions may mimic osteoid osteoma and vice versa, leading to misdiagnosis. Therefore, it is essential to understand these musculoskeletal diseases and their imaging findings to increase diagnostic accuracy, enable early treatment and prevent poor prognosis.
Highlights
Osteoid osteoma (OO) was first reported by Jaffe in 1935 [1] in a series of five cases; it is a painful, benign and common tumor, accounting for 3% of all bone neoplasms and 10–12% of benign lesions [2–5]
The nidus comprises an osteoid matrix with variable mineralization, osteoblasts and some osteoclast-type multinucleated giant cells interspersed by a loose fibrovascular stroma, with inflammatory changes and reactional bone formation around the lesion [8]
The typical clinical picture includes intermittent pain that becomes worse at night and is relieved by salicylates [4, 5]
Summary
Osteoid osteoma (OO) is a painful, benign and common bone tumor. Characteristic clinical and radiological findings are diagnostic, especially for lesions in typical locations. Osteoid osteoma (OO) is a painful, benign and common bone tumor. Characteristic clinical and radiological findings are diagnostic, especially for lesions in typical locations. Some OO cases present atypical location and unusual imaging findings that can lead to misdiagnosis. Many musculoskeletal conditions may present clinical and/or radiological features that mimic OO
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
