Osmium Tetroxide-t-Butyl Hydroperoxide

Abstract

(OsO4) [20816-12-0] O4Os (MW 254.20) InChI = 1S/4O.Os InChIKey = VUVGYHUDAICLFK-UHFFFAOYSA-N (TBHP) [75-91-2] C4H10O2 (MW 90.14) InChI = 1S/C4H10O2/c1-4(2,3)6-5/h5H,1-3H3 InChIKey = CIHOLLKRGTVIJN-UHFFFAOYSA-N (cis dihydroxylation of alkenes; osmylation) Physical Data: for 70% aq TBHP: bp 96 °C; mp −2.8 °C; d 0.935 g cm−3. See also Osmium Tetroxide. Solubility: TBHP: sol acetone, t-butyl alcohol. Form Supplied in: 70% aq TBHP (remaining water) in plastic bottle. Handling, Storage, and Precautions: TBHP is an eye and skin irritant. Safety goggles and gloves should be worn when handling TBHP solution. Avoid contamination of high-strength TBHP solution with strong acids and transition metal salts known to be good autooxidation catalysts (e.g. Mn, Fe, and Co). Never work with pure TBHP. Do not distill reaction mixtures containing TBHP without prior reduction with reducing agents such as Na2SO3. Store 70% aq TBHP in plastic containers below 38 °C but not much below 25 °C. Keep away from bright light and heat sources. See also Osmium Tetroxide.