Abstract
Objective: Structural elucidation of bioactive compounds from marine Sponge Suberites Carnosus (Johnston) by using Thin Layer Chromatography (TLC), Gas Chromatography-Mass Spectrometry (GC-MS), Fourier Transform Infrared Spectrometer (FTIR) techniques with respect to its pharmacological and biomedical properties.
 Methods: The sponge Suberites carnosus (Johnston) was collected during low tides from West Coast of Mumbai. Crude extract was obtained by taking 10 gram of sponge sample in10 ml of methanol. The preparative TLC (Thin Layer Chromatography) was performed by using Toluene: Ethyl acetate: Diethylamine (7:2:1) (v/v). The isolated compounds were subjected to GC-MS and FTIR analysis.
 Results: From the GC-MS and FTIR analysis, total ten compounds were identified. The GC-MS spectra correlate to the mass spectra. The structures of those compounds are 6-Fluoro 2-trifluromethylbenzoic acid,2,3-dichlorophenyl ester, Eicosane 3-cyclohexyl, Phosphine imide, P,P,P,-tris (p-chlorophenyl)-N-phenyl-, Dimethylhyl hexavinyl octasilsesquioxane, Hexanoicacid, hexadecyl ester, Hexadecanoic acid,2-hydroxy1-(hydroxymethyl)ethyl ester, 9, 19-Cyclolanostan-3-ol, acetate, (3β), Tetracosane, 3-ethyl-, 11, 14-Eicosadienoic acid, methyl ester, Triacontane, 11,20-didecyl-respectively.
 Conclusion: The nature and biological properties of the said compounds were determined and it was found that some of them act as a skin irritant. Some of them have fatty, metabolite, and irritant property, whereas some are act as masking and perfuming agents. Some compounds are highly toxic property, whereas others have an effect on health and environmental hazard. Some are highly corrosive in nature, whereas others are Cholesterol and chemotaxonomic significance.
Highlights
There is a worldwide interest in marine natural products as one of the few de novo sources of drug discovery [1]
The present study comprises an initial effort to assess the bioactivity of secondary metabolites from the marine subtidal sponges Suberites carnosus (Johnston) from Mumbai coasts and its extract was investigated for the presence of bioactive compounds
Ethical approval Ethical approval was sought from Maharashtra State Biodiversity Board, Nagpur, Maharashtra, India, for the collection of marine sponge Suberites carnosus [Johnston, 1842] from Mumbai coast to carry out the research
Summary
The sponge Suberites carnosus (Johnston) was collected during low tides from West Coast of Mumbai. Crude extract was obtained by taking 10 gram of sponge sample in ml of methanol. The preparative TLC (Thin Layer Chromatography) was performed by using Toluene: Ethyl acetate: Diethylamine (7:2:1) (v/v). The isolated compounds were subjected to GC-MS and FTIR analysis
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