Abstract
Organofluorine compounds are abundant in medicine and society-largely by human design and chemical synthesis, not de novo in Nature...
Highlights
Organofluorine compounds are abundant in medicine and society-largely by human design and chemical synthesis, not de novo in Nature
While by no means comprehensive, we hope this mini review provides a helpful resource for understanding the role of organofluorine compounds in 18F positron emission tomography (PET) imaging, bridging the health science and chemistry fields
18F PET imaging has proven its merit as a diagnostic tool, with its use in helping diagnose two pervasive illnesses, namely Alzheimer’s disease and cancer, making them exemplar cases for discussion
Summary
Organofluorine compounds are abundant in medicine and society-largely by human design and chemical synthesis, not de novo in Nature. With this has been major advancements, such as the ever-useful non-invasive positron emission tomography (PET) imaging technique [5,6]. We touch upon the synthesis of fluorine-18 labeled organofluorine compounds and discuss select usages in 18F PET imaging for two widespread diseases, namely cancer and Alzheimer’s disease.
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