Abstract
The enantioselective methods reported to date for carrying out conjugate additions of carbon- and heteroatom-centered nucleophiles to electron-deficient olefins, using small chiral organic molecules as catalysts, are reviewed. 1 Introduction 2 Organocatalytic Enantioselective Michael Reactions 2.1 Reactions Proceeding via Enamine Intermediates 2.2 Reactions Proceeding via Iminium Intermediates 2.3 Reactions Proceeding via Enamine and Iminium Intermediates- 2.4 Reactions Catalyzed by Chiral Thioureas 2.5 Reactions Catalyzed by Cinchona Alkaloids 2.6 Reactions under Phase-Transfer Conditions 2.7 Reactions Catalyzed by Other Organocatalysts 3 Organocatalytic Enantioselective Conjugate Friedel-Crafts Alkylations 4 Organocatalytic Enantioselective Conjugate Hydrogen-Transfer Reactions 5 Organocatalytic Enantioselective Hetero-Michael Reactions- 5.1 Sulfa-Michael Reactions 5.2 Aza-Michael Reactions 5.3 Oxa-Michael Reactions 5.4 Phospha-Michael Reactions 6 Miscellaneous Organocatalytic Enantioselective Conjugate Additions 7 Conclusions and Outlook
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
