Abstract
The first asymmetric sulfa-Michael addition of thiols to trans -3,3,3-trifluoropropenyl phenyl sulfone for the construction of a unique stereogenic center bearing a trifluoromethyl group and a sulfur atom has been achieved in high yields and moderate to good enantioselectivities with 1 mol % bifunctional amine–thiourea catalyst. The first asymmetric sulfa-Michael addition of thiols to trans -3,3,3-trifluoropropenyl phenyl sulfone for the construction of a unique stereogenic center bearing a trifluoromethyl group and a sulfur atom has been achieved in high yields and moderate to good enantioselectivities with 1 mol % bifunctional amine–thiourea catalyst.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
