Abstract
AbstractAs the analogues of indole bicyclic system, benzothiophenes are often overlooked in organic transformation, and synthetic methods developed mostly rely on the acidic protons at C2 or C3 position, known as C−H functionalization. Complementary to the structural modification of benzothiophenes, C−S bond cleavage can realize the skeleton reconstruction. Reduction of benzothiophenes always involves the C−S bond cleavage, especially in the hydrodesulfurization (HDS) of petroleum products. Beyond reductive desulfurization, although C−S bond cleavage of benzothiophenes has been achieved by diverse methodologies, there is no systematic review on such topic. Herein, transformation of benzothiophenes via C−S bond cleavage in organic synthesis will be presented along with briefly delineated mechanism.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
