Abstract
There have been many different methods of treatment for keloids. The fact that new methods are being sought constantly is evidence of their relative inadequacy. Some years ago it was suggested to us that systemic administration of redox-active substances might have an effect on keloids. The following report deals with experiences in 45 consecutive cases seen in the Dermatologic Out-Patient Clinic of Receiving Hospital. Material and Methods The use of tetrahydroxyquinone (THQ) was suggested by Mr. James V. Sheridan, working at that time at the Detroit Institute of Cancer Research. * This substance had been tested in animals and had been found free of toxic effects. It was fed by us to 20 female rats in doses ranging from 10 mg. per day to 180 mg. per day per rat for periods up to eight months. No harmful effects were observed. The animals gained weight regularly, and
Published Version
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