Abstract
Squamous cell carcinomas of the oral cavity usually arise from an oral precursor lesion. These lesions are graded into different categories according to their malignant transformation risk. Cytological criteria are more discernible and objective than the architectural ones, because most of general surgical pathologists who don't have sufficient daily practice on this subject may easily misinterpret the architectural criteria and underdiagnose OED as “hyperplastic epithelium, extensive keratosis, keratosis without dysplasia, verrucous hyperplasia, verrucous keratosis or pseudoepitheliomatous hyperplasia”. In the present study we aimed to clarify these architectural atypia criteria and emphasize the importance of recognising them. For this purpose; we present eight intraoral SCC cases which had previously diagnosed as OED or other than this. The previous biopsy slides were reassessed by different pathologists. It is concluded that the diagnosis of oral precursor lesions with predominantly architectural dysplasia is difficult.
Published Version
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