Abstract
A 19-year-old white woman was referred to the community health center with asymptomatic tumor related. Anamnesis revealed that the patient´s mother had undiagnosed congenital disease with multiple facial nodules. On general examination, cafe au lait macules on the neck and abdomen and a soft nodule in right forearm were observed. Intraoral examination revealed sessile nodular swelling in the dorsal surface of the tongue, involving middle and posterior thirds, with defined limits and purplish color, which was fibrous to palpation, about 6 cm in its largest diameter, and asymptomatic with evolution of approximately 3 years. Diagnostic hypothesis was neurofibroma related to neurofibromatosis. Incisional biopsy was performed on the tongue lesion. The histopathologic report and immunohistochemical study were conclusive for neurofibroma. Clinical and laboratory findings are suggestive of neurofibromatosis. Medical evaluation should be performed to confirm and define the type of neurofibromatosis. Neurofibromatosis is a frequent genetic condition with relevant oral manifestations in dental care.
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