ORAL MELANOMA INVOLVING GINGIVA AND PALATE

Abstract

A 67-year-old male farmer presented with the complaint of a slightly symptomatic spot in the mouth for the past 2 years. The medical history discussed no abnormalities. Extraoral examination revealed cervical lymphadenopathy on the left side and intraoral examination a blue-black sessile elevated mass with irregular borders, involving the attached vestibular gingiva of teeth 27 and 28, extending to the hard palate and measuring approximately 3.5 cm. Panoramic radiograph did not show bone involvement. A diagnostic hypothesis of oral melanoma was made, and an incisional biopsy was performed. Microscopic findings revealed a proliferation of densely pigmented pleomorphic cells, invading the subepithelial connective tissue in sheets or nests in an organoid fashion. Immunopositivity for S-100, Melan A, and HMB-45 confirmed the diagnosis of melanoma. The patient was referred to an oncology hospital, and, unfortunately, we have no information if he initiated the treatment. Financial Support: CAPES. A 67-year-old male farmer presented with the complaint of a slightly symptomatic spot in the mouth for the past 2 years. The medical history discussed no abnormalities. Extraoral examination revealed cervical lymphadenopathy on the left side and intraoral examination a blue-black sessile elevated mass with irregular borders, involving the attached vestibular gingiva of teeth 27 and 28, extending to the hard palate and measuring approximately 3.5 cm. Panoramic radiograph did not show bone involvement. A diagnostic hypothesis of oral melanoma was made, and an incisional biopsy was performed. Microscopic findings revealed a proliferation of densely pigmented pleomorphic cells, invading the subepithelial connective tissue in sheets or nests in an organoid fashion. Immunopositivity for S-100, Melan A, and HMB-45 confirmed the diagnosis of melanoma. The patient was referred to an oncology hospital, and, unfortunately, we have no information if he initiated the treatment. Financial Support: CAPES.