Abstract
Oral lymphoepithelial cyst (OLC) is a rare lesion of the mouth that develops within lymphoid tissue. The lesion presents as an asymptomatic, well-circumscribed, yellowish small submucosal nodule covered by normal overlying mucosa, usually located on the floor of the mouth or in the tongue. Histopathologic examination reveals a cyst lined by stratified squamous epithelium surrounded by lymphoid tissue. OLC should be treated with surgical excision and should not recur. A 30-year-old white female patient attended the Oral Medicine clinic complaining of a lesion on the tongue that had increased in size over the last year. Extraoral examination showed no abnormality. Intraoral examination revealed a symptomatic firm white-yellowish nodule on the posterolateral surface of the left side of the tongue. The diagnostic hypotheses were oral lymphoepithelial cyst and granular cell tumor. An excisional biopsy was performed and microscopic examination confirmed the diagnosis of OLC. After 1 year no recurrence was observed.
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