Abstract
The WHO Global Oral Health Status Report (2022) estimates that over 3.5 billion individuals worldwide have an oral disease. Most of the cases are dental caries, periodontal disease, tooth loss etc. Tooth loss will not only affect the balance of the oral environment but also cause negative effects on facial development and the patient's psychological condition. At present, The implement of oral stem cells to encourage tissue regeneration has become a hot trend. Among them, Periodontal Ligament Stem Cells (PDLSCs) and Dental Follicle Stem Cells (DFSCs) have been discovered it’s potential to promote tooth regeneration. Scientists proposed a variety of different treatment methods, including the use of advanced bioengineered technology to further target different oral diseases. So far, It is firmly established that oral stem cells have the potential to boost tissue regeneration.
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