Abstract
Chewing gums are mobile drug delivery systems. It is a potentially useful means of administering drugs either locally or systemically via, the oral cavity. Several ingredients are now incorporated in medicated chewing gum, e.g. Fluoride for prophylaxis of dental caries, chlorhexidine as local disinfectant, nicotine for smoking cessation, aspirin as an analgesic, and caffeine as a stay alert preparation. It was concluded that chewing gum is an excellent drug delivery system for self-medication as it is convenient and can be administered directly without water and they contain one or more active substances which are released by chewing and are intended to be used for local treatment of mouth diseases or systemic delivery after absorption through the buccal mucosa. Key-words : Medicated Chewing Gum, Mouth Diseases, Oral Drug Delivery System.
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