ORAL C.ALBICANS COLONIZATION AND NON-CANDIDA ALBICANS CANDIDA COLONIZATION AMONG UNIVERSITY STUDENTS, YEMEN

Abstract

Objectives: Candida albicans is diploid yeast that in some circumstances may cause oral or oropharyngeal infections. This investigation aimed to study the oral C. albicans colonization (OCC) and Non-Candida albicans Candida colonization (ONCACC) and risk factors of OCC in healthy University students. Methods: This cross sectional laboratory study was carried between January 2014 and July 2014. A total of 265 healthy students were included in this study, 131 males and 134 females. Demographic and clinical and risk factor variables were registered in predesigned questionnaire. Standard methods were used for collection oral specimens, culturing and identifying Candida species. Results: The crude rate of OCC was 17.7% and the crude rate of ONCACC was 29.1%. C. tropicalis and C. glabrata were the most common species isolated after C. albicans. Statistically significant association of OCC (< 0.05), was identified between the gender (male) (OR=3.7), smoking (OR=14.6), denture wearing (OR=6.2), dental bridge (OR=5.4), orthodontics (OR=2.5), the reduced saliva flow rate (OR=11.3), previous antibiotics users (OR=2.99), and Qat chewers (OR=5.2). Conclusion: Current study results are important for the development of strategies to eliminate these indicators of risk and significantly reduce Candida species colonization and oral Candida infections in young healthy adults and in general in Yemen community. The data also suggests that the prevalence rate of OCC was relatively high and it was affected by presence of prostheses, orthodontics, behaviors, xerostomia certain sociodemographic characteristics, which indicate the need for comprehensive, scheduled programs of healthcare educations. Peer Review History: Received 5 October 2017; Revised 29 October; Accepted 4 November, Available online 15 November 2017 UJPR follows the most transparent and toughest ‘Advanced OPEN peer review’ system. The identity of the authors and, reviewers will be known to each other. This transparent process will help to eradicate any possible malicious/purposeful interference by any person (publishing staff, reviewer, editor, author, etc) during peer review. As a result of this unique system, all reviewers will get their due recognition and respect, once their names are published in the papers. We expect that, by publishing peer review reports with published papers, will be helpful to many authors for drafting their article according to the specifications. Auhors will remove any error of their article and they will improve their article(s) according to the previous reports displayed with published article(s). The main purpose of it is ‘to improve the quality of a candidate manuscript’. Our reviewers check the ‘strength and weakness of a manuscript honestly’. There will increase in the perfection, and transparency. Received file: Reviewer's Comments: Average Peer review marks at initial stage: 6.5/10 Average Peer review marks at publication stage: 8.5/10 Reviewer(s) detail: Dr. Heba-Tallah Ahmed Mohamed Moustafa, Heliopolis University Cairo, Egypt, anasweety2003@yahoo.com Noha El Baghdady, MTI University, Cairo, Egypt, nohasalah21@yahoo.com Similar Articles: PREVALENCE AND ASSOCIATED FACTORS OF ORAL NON-CANDIDA ALBICANS CANDIDA CARRIAGE IN DENTURE WEARERS IN SANA'A CITY- YEMEN