Oral Administration of Magnesium Hydroxide to Subjects with Insulin-dependent Diabetes Mellitus: Effects on Magnesium and Potassium Levels and on Insulin Requirements

Abstract

Introduction: Diabetics lack potassium and magnesium. (Mg). Hypokalemia and hypomagnesemia cause vasoconstriction and glucose breakdown, so all hypomagnesemia diabetics should take K and Mg daily to prevent diabetic arterial disease. Methodology: 80 types 1 diabetes (T1-DM) patients were analyzed for parameters like K, Mg, Serum, Lipids, and HBA1c. After giving 1.7mg/dL blood Mg patients, 300mg Mg oxide daily for 3 months, the parameters were re-examined. 40 insulin-dependent diabetic men and women averaged 16.79 ± 4.00 years, Mg 2.94.38/dL. 30.3% had hypomagnesemia. Blood magnesium levels are inversely associated with age, diabetes length (P value 0.002) and other parameters and are favourably correlated with mean corpuscular volume, HDL, and platelet counts. Mg supplementation substantially lowered HBA1c. HBA1c started at 09.22%1.98%. Oral K and Mg tablets for three months lower it to 6.77%1.53%. (P0.003). it also lowered LDL, blood lipids, and total cholesterol in hypomagnesemia diabetics. Conclusion: Oral Mg intake in T1-DM patients improves glucose control, atherogenic lipid proportion, and therapeutic lipid component.