Optimizing the Approach and Clinical Outcomes of Women Undergoing Chronic Total Occlusion-Percutaneous Coronary Intervention

Abstract

Coronary artery disease remains a leading cause of morbidity and mortality globally, with chronic total occlusions (CTOs) representing a particularly challenging subset. Percutaneous coronary intervention (PCI) for CTOs has evolved significantly over the years, driven by advancements in equipment, techniques, and operator expertise. However, women have historically been underrepresented in clinical trials and guidelines, leading to a gap in an evidence-based management tailored to their specific needs, including in CTO-PCI. This review aims to explore the nuances of CTO-PCI in women, including anatomic considerations, procedural strategies, and clinical outcomes, with the goal of optimizing their care.