Abstract
Snake envenomation, particularly in Southeast Asia, often results in venom-induced consumption coagulopathy (VICC), a life-threatening condition characterized by severe bleeding and coagulopathy. Despite its clinical significance, management protocols for VICC remain under-researched, especially in resource-limited settings. A 30-year-old male was bitten by a green snake and presented with severe symptoms, including epistaxis, hematemesis, melena, hemoptysis, and hematuria. The diagnosis was confirmed with a 20-min whole blood clotting test. Initial treatment involved transfusion of thrombocyte concentrate (TC) and fresh frozen plasma (FFP), with specific anti-snake venom (ASV) administered 19 h postbite. VICC management is challenging. The initial administration of ASV is the key treatment to neutralize procoagulant toxins, but in the absence of ASV, the administration of FFP, TC, and packed red blood cells (PRCs) can be utilized to manage coagulopathy and as supportive measures based on patient’s clinical findings. The timing and combination of these treatments are crucial in optimizing the results. Proper diagnosis of VICC involves a thorough clinical assessment and diagnostic testing. Management of VICC requires prompt administration of ASV and management tailored to the patient’s condition and available resources. This case report aims to examine the management strategies of VICC, specifically the role of blood component transfusion, and highlight the challenges of treatment in resource-limited settings.
Published Version
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