Abstract

Relevance. The increasing prevalence of mild to moderate chronic generalized periodontitis depends on endogenous and exogenous factors. In most cases, these include factors such as fair oral hygiene, oral microbiota characteristics, increased loads on periodontium, malocclusion, smoking, history of systemic disorders, genetic predisposition, neuroses, etc. Despite the variety of available treatment protocols for mild to moderate chronic generalized periodontitis, the result has a short-term effect. Thus, searching for new treatment algorithms and creating improved medications with the necessary properties to stabilize the process and prolong remission in chronic periodontitis are relevant. The study aimed to evaluate the effectiveness of the comprehensive chronic periodontitis treatment with netilmicin ointment and propolis extract combined with diode laser, considering periodontal and immune statuses.Material and methods. The study involved 70 patients with mild and moderate chronic generalized periodontitis and 30 controls without signs of inflammatory periodontal diseases (IPD). The main group consisted of 50 patients with IPD, who had comprehensive treatment with the ointment based on netilmicin and propolis extract and antiinflammatory therapy using the Doctor Smile diode laser. The comparison group comprised 20 patients whose treatment protocol did not include laser treatment. We conducted a clinical and immunological study of patients before and after the treatment.Results. The comprehensive treatment evaluation, including clinical and immunological analysis, revealed a significant improvement in the parameters when using a combination of ointment with netilmicin/propolis extract and laser therapy, compared to standard non-surgical treatment.Conclusion. The clinical and immunological analysis of the comprehensive treatment of patients with chronic periodontitis has established the advantage of the combined use of non-surgical treatment and physiotherapy procedures.

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