Optimization of a YAP(Ce) prompt X-ray camera for imaging with spot scanning proton beams at clinical dose levels

Abstract

Prompt secondary electron bremsstrahlung X-ray (prompt X-ray) imaging using a low-energy X-ray camera is a promising method for observing the beam shape from outside a subject. However, it has sometimes been necessary to conduct such imaging at a higher dose than the clinical level to acquire images with acceptable quality. To solve this problem, we optimized a prompt X-ray imaging system to use for spot scanning proton therapy system. The new camera had more than one order higher sensitivity to image several types of beams, including those at the clinical dose level. The optimized prompt X-ray imaging system uses a 4 mm diameter pinhole collimator to increase sensitivity, and it is combined with a larger YAP(Ce) scintillator to increase the magnification ratio and thus improve spatial resolution. We used a list-mode data-acquisition system with high count rate capability. Prompt X-ray images were acquired by irradiating a water phantom with proton beams from the spot scanning proton therapy system. Measurements were taken for pencil beams, spread-out Bragg peak (SOBP) beams, and a beam utilized in actual clinical therapy. For all of the beams, we could measure scanning spot images within a spill and evaluate the ranges for the accumulated images at the clinical dose level. From the list-mode data, we measured the temporarily altered positions of the scanning beams as well as the accumulations of the prompt X-ray images. The optimized prompt X-ray imaging system could improve sensitivity while maintaining better spatial resolution. The new system realized prompt X-ray imaging at the clinical dose level and holds promise for future clinical imaging of prompt X-rays.