Abstract
10 (3–63) 19 (10–47) 0.011 About 2 weeks post randomisation, 94% of infants had successfully weaned in the ‘pressure’ group compared with 67% in the ‘time off’ group. A week later, 97% in the pressure group had weaned compared with 81% in the time off group. A Kaplan–Meier graph on ‘time to wean’ for all patients in both groups was drawn and generated a log rank test with a highly significant p value of <0.001 for differences in median time to wean. Infants weaned via pressure reduction faster [pressure= 36 h (95% CI: 31.3 to 50.7) vs. time off=352 h (95% CI: 209.5 to 494.5)]. Conclusion: For VLBW infants, the gradual reduction in nCPAP pressure may facilitate more rapid respiratory weaning compared with periods of increasing time spent off nCPAP. Reference [1] Sreenan C, Lemke RP, Hudson-Mason A, Osiovich H. High-flow nasal cannula in the management of apnea of prematurity: a comparison with conventional nasal continuous positive airway pressure. Pediatrics 2001;107:
Published Version
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