Abstract
Abstract A design analysis is presented to obtain the prosthetic tri-leaflet aortic valve leaflet's optimum design parameters (leaflet curvatures and thickness normalized with respect to the valve ring size), to effect a smooth washout, minimize leaflet stress, facilitate opening of the valve at a reasonable value of the transmembrane pressure and ensure an adequate lifetime (for a given leaflet material's fatigue data). Two alternative optimum designs (characterized by the geometrical parameters of the cusp) are obtained to satisfy the design criteria of smooth washout and minimal leaflet stress. Then, for a specific blood-compatible valve leaflet material (Avcothane-51), † the leaflet thicknesses of the two design candidates are determined to satisfy the criteria of minimal opening pressure and adequate lifetime. The fabrication and in vitro testing of the optimum designs are discussed; to date the optimum designs have performed more than 350 million cycles in in vitro tests.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call