Abstract

The human rotavirus titer was optimal at an infection cell density of about 4–8 × 104 cells cm−2 in monkey kidney cell cultures. The highest viral titers (3.8 × 107 TCID50 ml−1 and 3.7 × 107 TCID50 ml−1) were obtained at an multiplicity of infection of 0.05 in well plate and T-flask, respectively.

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