Abstract

We propose optically controlled micromanipulation tools that operate in sealed environments. The micromanipulator arm has probes to grasp microobjects and a handle to rotate the arm on its long axis. When a laser beam is focused on the handle and scanned linearly on the focal plane, the handle inclines toward the focus, rotating the arm on its long axis for probes to grasp a microobject. Rotation enable the microobject to be grasped separately from a substrate. Micromanipulators, fabricated by using two-photon microstereolithography, can catch microparticles in three dimensions, and a single manipulator arm with twin probes has been used to slide a microparticle on a glass substrate. Such optically controlled micromanipulators are potentially versatile, powerful tools for micro total analysis in biological applications.

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