Abstract
By crystallization of ΔΛ-[Co(aet)(en)2][ClO4]2 in the presence of Δ-Na[Co(edta)]·3H2O or Na2(D-tart)·2H2O [aet = 2-aminoethanethiolate(1–), en = ethylenediamine, edta = ethylenediaminetetraacetate(4–) and D-tart =(RR)-tartrate(2–)] the Δ-aet complex always appears as the first crop. The mechanism can be best explained by use of a ternary solubility isotherm: a shift of the eutectic point on the central racemic line into the optically active region is caused by the active cosolute (or solvent); the larger the shift the higher is the percentage resolution. This isotherm has also clarified that the solubility difference between the enantiomers in the binary system is not relevant to the optical resolution. This resolution mechanism is applicable to conglomerates with rapid racemization rates.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Journal of the Chemical Society, Dalton Transactions
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
