Abstract
The application of the simulated moving bed adsorption (SMBA) technique to optical resolution using eight columns packed with chiral stationary phases was studied. The SMBA system was compared with the conventional batch system, and it was concluded that the former is better from the point of productivity and solvent recovery. In addition, it was shown that an optimum particle size of the chiral phase to attain the maximum productivity exists if a certain upper limit of the pressure drop is assumed.
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